32P-Post-labelling method improvements for aromatic compound-related molecular epidemiology studies
نویسندگان
چکیده
منابع مشابه
32P-Post-labelling method improvements for aromatic compound-related molecular epidemiology studies.
The (32)P-post-labelling assay has emerged as a major tool for detecting bulky DNA adducts in subjects exposed to carcinogens, especially aromatic compounds. However, the (32)P-post-labelling protocol still requires the use of high amounts of radioactivity, i.e. 25-50 muCi per sample, an obstacle that limits its use in large studies. The characterization of the DNA adducts measured is also limi...
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ژورنال
عنوان ژورنال: Mutagenesis
سال: 2007
ISSN: 0267-8357,1464-3804
DOI: 10.1093/mutage/gem030